STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
optnOptineurin. (525 aa)    
Predicted Functional Partners:
tbk1
TANK-binding kinase 1.
    
 0.994
gabarap
Gamma-aminobutyric acid receptor-associated protein.
   
 0.978
LOC105929691
GABA(A) receptor-associated protein like 2.
   
 0.978
LOC105934954
Zgc:92606.
   
 0.971
ikbke
Inhibitor of nuclear factor kappa-B kinase subunit epsilon.
    
 0.969
rb1cc1
RB1-inducible coiled-coil 1.
    
 
 0.941
rps27a
Ribosomal protein S27a.
   
 0.929
tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.898
tab2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.898
map1lc3a
Microtubule-associated protein 1 light chain 3 alpha.
   
 0.889
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.