STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gbx2Gastrulation brain homeobox 2. (348 aa)    
Predicted Functional Partners:
ENSFHEP00000000835
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
  
 0.637
anapc1
Anaphase promoting complex subunit 1.
      
 0.614
wnt1
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
 
 0.603
nek2
Serine/threonine-protein kinase Nek2.
      
 0.595
LOC105933766
Forkhead box protein I1.
    
 
 0.559
rhbdl3
Rhomboid-related protein 3; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.
   
 
 0.525
LOC105917541
Orthodenticle homeobox 2b.
      
0.491
LOC105936055
Pre-B-cell leukemia homeobox 2.
    
 0.489
pbx3
Pre-B-cell leukemia transcription factor 3.
    
 0.489
LOC105916687
Pre-B-cell leukemia homeobox 1a.
    
 0.489
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.