STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ap1s3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (177 aa)    
Predicted Functional Partners:
ap1g1
AP-1 complex subunit gamma.
    
 0.990
ap1m1
AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
    
 0.985
LOC105930268
AP-1 complex subunit gamma.
    
 0.982
gak
Cyclin G associated kinase.
   
 
 0.981
ap1m2
AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
    
 0.979
LOC105936949
Adaptor related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family.
    
 0.979
ENSFHEP00000014877
B2-adapt-app_C domain-containing protein.
    
 0.975
AP1S2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
  
  
 
0.965
ap1s2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
  
  
 
0.962
ENSFHEP00000014747
Adaptor related protein complex 1 subunit beta 1.
    
 0.960
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.