pmvk protein (Fundulus heteroclitus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

pmvk

Phosphomevalonate kinase. (200 aa)

Predicted Functional Partners:

mvd

0.987

ENSFHEP00000012152

0.983

idi1

0.739

grb2

0.730

pdia6

0.683

LOC105917111

0.673

LOC105928432

0.651

LOC105928434

0.651

itpka

0.637

dhcr24

0.627

Your Current Organism:

Fundulus heteroclitus

NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSFHEP00000012152	LOC105917111	ENSFHEP00000012152	ENSFHEP00000007962	GHMP_kinases_C domain-containing protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.948
ENSFHEP00000012152	LOC105928432	ENSFHEP00000012152	ENSFHEP00000019409	GHMP_kinases_C domain-containing protein.	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	0.682
ENSFHEP00000012152	LOC105928434	ENSFHEP00000012152	ENSFHEP00000033881	GHMP_kinases_C domain-containing protein.	Uncharacterized protein.	0.682
ENSFHEP00000012152	dhcr24	ENSFHEP00000012152	ENSFHEP00000000320	GHMP_kinases_C domain-containing protein.	24-dehydrocholesterol reductase.	0.595
ENSFHEP00000012152	idi1	ENSFHEP00000012152	ENSFHEP00000032158	GHMP_kinases_C domain-containing protein.	Isopentenyl-diphosphate delta isomerase 1.	0.855
ENSFHEP00000012152	mvd	ENSFHEP00000012152	ENSFHEP00000019470	GHMP_kinases_C domain-containing protein.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.997
ENSFHEP00000012152	pmvk	ENSFHEP00000012152	ENSFHEP00000033723	GHMP_kinases_C domain-containing protein.	Phosphomevalonate kinase.	0.983
LOC105917111	ENSFHEP00000012152	ENSFHEP00000007962	ENSFHEP00000012152	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	GHMP_kinases_C domain-containing protein.	0.948
LOC105917111	LOC105928432	ENSFHEP00000007962	ENSFHEP00000019409	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	0.956
LOC105917111	LOC105928434	ENSFHEP00000007962	ENSFHEP00000033881	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Uncharacterized protein.	0.956
LOC105917111	dhcr24	ENSFHEP00000007962	ENSFHEP00000000320	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	24-dehydrocholesterol reductase.	0.721
LOC105917111	idi1	ENSFHEP00000007962	ENSFHEP00000032158	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Isopentenyl-diphosphate delta isomerase 1.	0.984
LOC105917111	mvd	ENSFHEP00000007962	ENSFHEP00000019470	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.926
LOC105917111	pmvk	ENSFHEP00000007962	ENSFHEP00000033723	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Phosphomevalonate kinase.	0.673
LOC105928432	ENSFHEP00000012152	ENSFHEP00000019409	ENSFHEP00000012152	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	GHMP_kinases_C domain-containing protein.	0.682
LOC105928432	LOC105917111	ENSFHEP00000019409	ENSFHEP00000007962	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.956
LOC105928432	dhcr24	ENSFHEP00000019409	ENSFHEP00000000320	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	24-dehydrocholesterol reductase.	0.534
LOC105928432	idi1	ENSFHEP00000019409	ENSFHEP00000032158	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	Isopentenyl-diphosphate delta isomerase 1.	0.976
LOC105928432	mvd	ENSFHEP00000019409	ENSFHEP00000019470	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes.	0.984
LOC105928432	pmvk	ENSFHEP00000019409	ENSFHEP00000033723	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	Phosphomevalonate kinase.	0.651