STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OTP-2Orthopedia homeobox b. (328 aa)    
Predicted Functional Partners:
nr4a2
Nuclear receptor subfamily 4, group A, member 2b.
      
 0.589
LOC105935451
Nescient helix loop helix 2.
   
 0.505
LOC105924010
Uncharacterized protein.
    
 0.501
srf
Serum response factor b.
    
 0.501
LOC105938673
LIM domain binding 1a.
    
 0.453
ldb1
LIM-domain binding 1b.
    
 0.453
LOC105931932
LIM domain binding 2a.
    
 0.453
ENSFHEP00000016585
BHLH domain-containing protein.
   
 0.451
sim1
Uncharacterized protein.
   
  
 0.425
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.