STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nek2Serine/threonine-protein kinase Nek2. (445 aa)    
Predicted Functional Partners:
LOC105917492
BUB1 mitotic checkpoint serine/threonine kinase Bb.
   
 0.998
cdc20
Cell division cycle 20 homolog.
   
 0.998
anapc4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
    
 0.996
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.992
ENSFHEP00000027531
Uncharacterized protein.
    
 0.991
FZR1
Fizzy/cell division cycle 20 related 1a.
   
 0.990
LOC105925280
Fizzy/cell division cycle 20 related 1b.
   
 0.990
ENSFHEP00000010787
BUB1 N-terminal domain-containing protein.
   
 0.987
LOC105934358
Uncharacterized protein.
   
 0.987
anapc1
Anaphase promoting complex subunit 1.
    
 0.984
Your Current Organism:
Fundulus heteroclitus
NCBI taxonomy Id: 8078
Other names: Atlantic killifish, F. heteroclitus, killifish, mummichog
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