Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103462148Uncharacterized protein. (375 aa)    
Predicted Functional Partners:
LOC103479056
Profilin; Belongs to the profilin family.
   
 0.954
LOC103463469
Profilin; Belongs to the profilin family.
   
 0.954
LOC103460828
Profilin; Belongs to the profilin family.
   
 0.954
Cfl2
Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.
   
 0.952
Cfl1
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 0.952
arpc2
Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.952
wasf1
WASP family member 1.
    
 0.950
wasf2
WASP family member 2.
    
 0.950
vcl
Vinculin b.
   
 0.947
iqgap1
IQ motif containing GTPase activating protein 1.
    
 0.947
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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