STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLK1Serine/threonine-protein kinase PLK. (581 aa)    
Predicted Functional Partners:
CDC25B
Cell division cycle 25B.
   
 0.991
ccnb3
Cyclin B3; Belongs to the cyclin family.
   
 0.991
FZR1
Fizzy/cell division cycle 20 related 1a.
   
 0.989
LOC103474790
Cyclin N-terminal domain containing 2; Belongs to the cyclin family.
   
 0.988
ccnb1
Cyclin B1; Belongs to the cyclin family.
   
 0.988
anapc1
Anaphase promoting complex subunit 1.
   
 0.986
cdc16
Cell division cycle 16 homolog (S. cerevisiae).
   
 0.982
cdc27
Cell division cycle 27.
   
 0.981
cdc23
CDC23 (cell division cycle 23, yeast, homolog).
   
 0.980
cdk1
Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.
   
0.976
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.