STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000000078Sorbin and SH3 domain containing 2a. (1096 aa)    
Predicted Functional Partners:
vcl
Vinculin b.
   
 0.868
LOC103476978
Vinculin a.
   
 0.868
vta1
Vesicle (multivesicular body) trafficking 1.
    
 
 0.783
LOC103481546
GTP cyclohydrolase 2.
    
   0.653
gch1
GTP cyclohydrolase 1.
    
   0.653
LOC103477907
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 
 0.606
LOC103476312
Uncharacterized protein.
    
 
 0.606
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 
 0.606
fgf17
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.583
LOC103464969
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family.
    
 0.553
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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