STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tlr3Toll-like receptor 3; Belongs to the Toll-like receptor family. (924 aa)    
Predicted Functional Partners:
LOC103479366
TRIF-NTD domain-containing protein.
   
 0.949
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.883
unc93b1
Unc-93 homolog B1, TLR signaling regulator.
    
 0.810
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.770
irf7
Interferon regulatory factor 7.
   
 
 0.670
tradd
Tnfrsf1a-associated via death domain.
    
 
 0.632
irak4
Interleukin-1 receptor-associated kinase 4.
   
 0.609
LOC103470751
Protein kinase domain-containing protein.
    
 0.580
LOC103479635
Death domain-containing protein.
   
 0.579
LOC103481249
Interferon regulatory factor 3.
   
 
 0.573
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (28%) [HD]