Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103461041Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (282 aa)    
Predicted Functional Partners:
xiap
X-linked inhibitor of apoptosis.
   
 0.989
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
0.986
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 0.977
gsdme
Gasdermin Eb.
    
 0.974
birc2
Baculoviral IAP repeat containing 2.
   
 0.973
sptan1
Spectrin alpha, non-erythrocytic 1.
   
 0.970
LOC103481969
Baculoviral IAP repeat containing 5a.
   
 0.965
ENSPREP00000031693
Gasdermin domain-containing protein.
    
 0.964
LOC103478931
Uncharacterized protein; Belongs to the peptidase C14A family.
  
0.962
LOC103459939
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
  
0.959
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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