Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000000143Uncharacterized protein. (194 aa)    
Predicted Functional Partners:
Sh3yl1
SH3 and SYLF domain containing 1.
    
   0.897
ficd
FIC domain containing.
      
 0.602
LOC103475657
ENTH domain-containing protein.
     
 0.575
clint1
Clathrin interactor 1a.
     
 0.575
vta1
Vesicle (multivesicular body) trafficking 1.
    
   0.560
pum1
Pumilio RNA-binding family member 1.
     
  0.540
pum2
Pumilio RNA-binding family member 2.
     
  0.540
Pum2
Uncharacterized protein.
     
  0.540
cwc22
CWC22 spliceosome associated protein homolog.
     
 0.507
sart3
Spliceosome associated factor 3, U4/U6 recycling protein.
      
 0.488
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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