STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
parnPoly(A)-specific ribonuclease (deadenylation nuclease). (683 aa)    
Predicted Functional Partners:
dcp2
Decapping mRNA 2.
     
 0.774
exosc5
Exosome component 5.
     
 0.726
exosc6
Exosome component 6.
     
 0.709
exosc3
Exosome component 3.
     
 0.704
exosc4
Exosome component 4.
     
 0.701
ENSPREP00000026599
Exosome component 7.
     
 0.699
dis3l2
DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
   
 
 0.697
dis3
DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family.
   
 
 0.682
khsrp
KH-type splicing regulatory protein.
   
 0.678
fubp1
Far upstream element (FUSE) binding protein 1.
   
 0.678
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.