Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
man2b1Alpha-mannosidase. (1029 aa)    
Predicted Functional Partners:
man2c1
Mannosidase, alpha, class 2C, member 1.
     
0.949
man2b2
Alpha-mannosidase.
     
0.902
naga
Alpha-galactosidase.
   
 
 0.682
gla
Alpha-galactosidase.
   
 
 0.682
siae
Sialic acid acetylesterase.
    
 
 0.661
manba
Mannosidase, beta A, lysosomal.
   
 
 0.636
LOC103472139
Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase b.
   
  
 0.609
hspa13
Heat shock protein 70 family, member 13.
    
 
 0.591
gusb
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
   
 
 0.549
tectb
Tectorin beta.
      
 0.533
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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