Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Cacna1aUncharacterized protein. (426 aa)    
Predicted Functional Partners:
cacna2d2
Calcium channel, voltage-dependent, alpha 2/delta subunit 2a.
   
 0.881
Unc79
Uncharacterized protein.
   
 0.878
LOC103464608
Calcium channel, voltage-dependent, alpha 2/delta subunit 2b.
   
 0.819
LOC103459225
Calcium channel, voltage-dependent, alpha 2/delta subunit 1a.
   
 0.818
cacna2d1
Calcium voltage-gated channel auxiliary subunit alpha2delta 1.
   
 0.818
ENSPREP00000000270
Ca_chan_IQ domain-containing protein.
 
      0.800
ENSPREP00000002713
VWFA domain-containing protein.
   
 0.736
CACNA2D4
Calcium voltage-gated channel auxiliary subunit alpha2delta 4.
   
 0.736
ENSPREP00000006262
VGCC_alpha2 domain-containing protein.
   
 0.736
ENSPREP00000008517
VGCC_alpha2 domain-containing protein.
   
 0.736
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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