Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSPREP00000000280General transcription factor IIIAa. (328 aa)    
Predicted Functional Partners:
GTF3C1
General transcription factor IIIC subunit 1.
    
 0.906
bdp1
SANT domain-containing protein.
    
 0.841
LOC103458137
TFIIB-type domain-containing protein.
   
 0.802
ENSPREP00000017888
BRF1 RNA polymerase III transcription initiation factor subunit b.
   
 0.802
gtf3c3
General transcription factor IIIC, polypeptide 3.
    
 0.773
polr2l
Polymerase (RNA) II (DNA directed) polypeptide L.
    
 0.734
polr2f
Polymerase (RNA) II (DNA directed) polypeptide F.
   
 0.731
abhd10
Transgelin 3b.
   
 
 0.665
gsx1
GS homeobox 1.
    
 
 0.661
polr1c
RNA polymerase I and III subunit C.
   
 0.657
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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