Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
xpaXeroderma pigmentosum, complementation group A. (275 aa)    
Predicted Functional Partners:
ercc1
Excision repair cross-complementation group 1.
    
 0.999
ercc3
Excision repair cross-complementation group 3.
    
 0.999
ercc4
Excision repair cross-complementation group 4.
    
 0.998
ercc2
Excision repair cross-complementation group 2.
    
 0.994
rpa3
Replication protein A3.
    
 0.992
xpc
Xeroderma pigmentosum, complementation group C.
    
 0.991
gtf2h5
General transcription factor IIH, polypeptide 5.
    
 0.988
ercc6
Excision repair cross-complementation group 6.
    
 0.986
fancm
Uncharacterized protein.
    
 0.983
ddb1
Damage-specific DNA binding protein 1.
    
 0.978
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.