LOC103464091 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LOC103464091

CREB binding protein a. (2371 aa)

Predicted Functional Partners:

LOC103468460

0.998

LOC103482005

0.998

tp53

0.997

kat2b

0.990

sp1

0.990

kat2a

0.990

ctnnb1

0.973

LOC103481249

0.973

carm1

0.960

foxm1

0.959

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103464091	LOC103468460	ENSPREP00000000408	ENSPREP00000026558	CREB binding protein a.	E1A binding protein p300 b.	0.998
LOC103464091	LOC103481249	ENSPREP00000000408	ENSPREP00000032515	CREB binding protein a.	Interferon regulatory factor 3.	0.973
LOC103464091	LOC103482005	ENSPREP00000000408	ENSPREP00000030842	CREB binding protein a.	E1A binding protein p300 a.	0.998
LOC103464091	carm1	ENSPREP00000000408	ENSPREP00000010964	CREB binding protein a.	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.960
LOC103464091	ctnnb1	ENSPREP00000000408	ENSPREP00000019419	CREB binding protein a.	Catenin (cadherin-associated protein), beta 1.	0.973
LOC103464091	foxm1	ENSPREP00000000408	ENSPREP00000033036	CREB binding protein a.	Forkhead box M1.	0.959
LOC103464091	kat2a	ENSPREP00000000408	ENSPREP00000015085	CREB binding protein a.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.990
LOC103464091	kat2b	ENSPREP00000000408	ENSPREP00000009570	CREB binding protein a.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.990
LOC103464091	sp1	ENSPREP00000000408	ENSPREP00000011446	CREB binding protein a.	Sp1 transcription factor.	0.990
LOC103464091	tp53	ENSPREP00000000408	ENSPREP00000019676	CREB binding protein a.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.997
LOC103468460	LOC103464091	ENSPREP00000026558	ENSPREP00000000408	E1A binding protein p300 b.	CREB binding protein a.	0.998
LOC103468460	LOC103481249	ENSPREP00000026558	ENSPREP00000032515	E1A binding protein p300 b.	Interferon regulatory factor 3.	0.964
LOC103468460	LOC103482005	ENSPREP00000026558	ENSPREP00000030842	E1A binding protein p300 b.	E1A binding protein p300 a.	0.902
LOC103468460	carm1	ENSPREP00000026558	ENSPREP00000010964	E1A binding protein p300 b.	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.973
LOC103468460	ctnnb1	ENSPREP00000026558	ENSPREP00000019419	E1A binding protein p300 b.	Catenin (cadherin-associated protein), beta 1.	0.965
LOC103468460	foxm1	ENSPREP00000026558	ENSPREP00000033036	E1A binding protein p300 b.	Forkhead box M1.	0.889
LOC103468460	kat2a	ENSPREP00000026558	ENSPREP00000015085	E1A binding protein p300 b.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.991
LOC103468460	kat2b	ENSPREP00000026558	ENSPREP00000009570	E1A binding protein p300 b.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.991
LOC103468460	sp1	ENSPREP00000026558	ENSPREP00000011446	E1A binding protein p300 b.	Sp1 transcription factor.	0.993
LOC103468460	tp53	ENSPREP00000026558	ENSPREP00000019676	E1A binding protein p300 b.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.997