Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nanos3Nanos homolog 3; Belongs to the nanos family. (209 aa)    
Predicted Functional Partners:
ENSPREP00000009754
DND microRNA-mediated repression inhibitor 1.
    
 
 0.941
dazl
Deleted in azoospermia-like.
    
 
 0.855
ENSPREP00000033092
Uncharacterized protein.
      
 0.718
piwil1
Piwi-like RNA-mediated gene silencing 1; Belongs to the argonaute family.
   
 
 0.714
ENSPREP00000028080
Piwi domain-containing protein.
   
 
 0.714
zbtb16
Zinc finger and BTB domain containing 16a.
    
 
 0.713
ddx4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; Belongs to the DEAD box helicase family.
    
 
 0.694
prdm14
PR domain containing 14.
    
 
 0.676
Lin28a
CCHC-type domain-containing protein.
   
  
 0.671
atat1
Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...]
      
 0.671
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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