Sirt7 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

Sirt7

Uncharacterized protein. (134 aa)

Predicted Functional Partners:

ddb1

0.937

polr1a

0.905

WDR77

0.901

LOC103460486

0.811

ubtf

0.811

sirt1

0.808

LOC103475730

0.803

fbl

0.759

sgsh

0.698

LOC103465438

0.696

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103460486	Sirt7	ENSPREP00000001918	ENSPREP00000000575	Upstream binding transcription factor, like.	Uncharacterized protein.	0.811
LOC103460486	ddb1	ENSPREP00000001918	ENSPREP00000006475	Upstream binding transcription factor, like.	Damage-specific DNA binding protein 1.	0.407
LOC103460486	polr1a	ENSPREP00000001918	ENSPREP00000003406	Upstream binding transcription factor, like.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.881
LOC103465438	Sirt7	ENSPREP00000026964	ENSPREP00000000575	ETS transcription factor ELK4.	Uncharacterized protein.	0.696
LOC103475730	Sirt7	ENSPREP00000031463	ENSPREP00000000575	Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family.	Uncharacterized protein.	0.803
LOC103475730	sirt1	ENSPREP00000031463	ENSPREP00000003960	Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family.	Sirtuin 1.	0.406
Sirt7	LOC103460486	ENSPREP00000000575	ENSPREP00000001918	Uncharacterized protein.	Upstream binding transcription factor, like.	0.811
Sirt7	LOC103465438	ENSPREP00000000575	ENSPREP00000026964	Uncharacterized protein.	ETS transcription factor ELK4.	0.696
Sirt7	LOC103475730	ENSPREP00000000575	ENSPREP00000031463	Uncharacterized protein.	Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.803
Sirt7	WDR77	ENSPREP00000000575	ENSPREP00000013214	Uncharacterized protein.	WD repeat domain 77.	0.901
Sirt7	ddb1	ENSPREP00000000575	ENSPREP00000006475	Uncharacterized protein.	Damage-specific DNA binding protein 1.	0.937
Sirt7	fbl	ENSPREP00000000575	ENSPREP00000026890	Uncharacterized protein.	Fibrillarin.	0.759
Sirt7	polr1a	ENSPREP00000000575	ENSPREP00000003406	Uncharacterized protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.905
Sirt7	sgsh	ENSPREP00000000575	ENSPREP00000000571	Uncharacterized protein.	N-sulfoglucosamine sulfohydrolase (sulfamidase).	0.698
Sirt7	sirt1	ENSPREP00000000575	ENSPREP00000003960	Uncharacterized protein.	Sirtuin 1.	0.808
Sirt7	ubtf	ENSPREP00000000575	ENSPREP00000014208	Uncharacterized protein.	Upstream binding transcription factor.	0.811
WDR77	Sirt7	ENSPREP00000013214	ENSPREP00000000575	WD repeat domain 77.	Uncharacterized protein.	0.901
ddb1	LOC103460486	ENSPREP00000006475	ENSPREP00000001918	Damage-specific DNA binding protein 1.	Upstream binding transcription factor, like.	0.407
ddb1	Sirt7	ENSPREP00000006475	ENSPREP00000000575	Damage-specific DNA binding protein 1.	Uncharacterized protein.	0.937
ddb1	sirt1	ENSPREP00000006475	ENSPREP00000003960	Damage-specific DNA binding protein 1.	Sirtuin 1.	0.484