Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMC6Transmembrane channel-like protein. (717 aa)    
Predicted Functional Partners:
Tmc3
Si:dkey-15b23.3.
      
 0.580
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
    
 
 0.538
skiv2l
SKI2 homolog, superkiller viralicidic activity 2-like.
    
 0.537
tcte1
T-complex-associated-testis-expressed 1.
    
 0.506
efhb
Uncharacterized protein.
    
 
 0.505
kntc1
Kinetochore associated 1.
      
 0.496
CEP164
Centrosomal protein 164.
   
 0.430
clrn3
Clarin 3.
     
 0.429
raver2
Ribonucleoprotein, PTB-binding 2.
    
 
 0.414
LOC103465435
Synaptogyrin.
      
 0.409
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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