Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103464796ATP-binding cassette, sub-family C (CFTR/MRP), member 6a. (1518 aa)    
Predicted Functional Partners:
ABCC1
ATP binding cassette subfamily C member 1.
  
  
 
0.902
ENSPREP00000002302
ATP-binding cassette, sub-family G (WHITE), member 2d.
   
 0.661
LOC103480848
ATP-binding cassette, sub-family G (WHITE), member 2a.
   
 0.618
LOC103462236
ATP-binding cassette, sub-family G (WHITE), member 2c.
   
 0.556
LOC103459623
PDZ domain containing 1.
    
 0.542
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.539
acox3
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
   
 
 0.528
gopc
Golgi-associated PDZ and coiled-coil motif containing.
    
 0.524
usp10
Ubiquitin carboxyl-terminal hydrolase.
    
  0.519
abcg4
ATP-binding cassette, sub-family G (WHITE), member 4a.
   
 0.518
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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