Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000000775Uncharacterized protein. (175 aa)    
Predicted Functional Partners:
sppl3
Signal peptide peptidase 3.
      
 0.670
Wdr74
WD repeat domain 74.
      
 0.664
ranbp1
RAN binding protein 1.
      
 0.599
klhl14
Kelch-like family member 14.
      
 0.596
SYDE2
Synapse defective Rho GTPase homolog 2.
      
 0.593
LOC103469125
Cerebellar degeneration-related protein 2-like.
      
 0.592
cdr2l
Uncharacterized protein.
      
 0.592
ankmy2
Ankyrin repeat and MYND domain containing 2a.
      
 0.581
LOC103469251
FAM20C golgi associated secretory pathway kinase a.
      
 0.570
disp3
Dispatched RND transporter family member 3.
   
  
 0.568
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (24%) [HD]