Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
srgap1SLIT-ROBO Rho GTPase activating protein 1a. (1094 aa)    
Predicted Functional Partners:
ENSPREP00000015831
Uncharacterized protein.
   
 0.661
ENSPREP00000015870
Uncharacterized protein.
   
 0.661
ENSPREP00000015917
EH domain-containing protein.
   
 0.661
itsn2
Intersectin 2a.
   
 0.661
nckipsd
NCK interacting protein with SH3 domain.
    
 
 0.537
ktn1
Kinectin 1.
      
 0.516
CDC42
Cell division cycle 42.
    
 0.515
LOC103465423
Cell division cycle 42.
    
 0.515
ddx43
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43; Belongs to the DEAD box helicase family.
   
  
 0.514
fam72a
Family with sequence similarity 72 member B.
      
 0.505
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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