Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF220Uncharacterized protein. (239 aa)    
Predicted Functional Partners:
ENSPREP00000000846
Ring finger protein 220a.
 
      0.900
LOC103464120
RING-type domain-containing protein.
 
      0.900
zc4h2
Zinc finger, C4H2 domain containing.
    
 
 0.879
usp7
Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.
    
 0.539
RPL27A
Ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family.
    
   0.511
fbxo3
F-box protein 3.
      
 0.462
hibch
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.
    
   0.459
LOC103477297
VRK serine/threonine kinase 2.
    
 0.459
vrk1
VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily.
    
 0.459
mysm1
Myb-like, SWIRM and MPN domains 1.
    
 0.449
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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