Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
znf330Zinc finger protein 330. (316 aa)    
Predicted Functional Partners:
gsc
Goosecoid.
    
   0.917
clpx
Caseinolytic mitochondrial matrix peptidase chaperone subunit b.
    
   0.843
rwdd4
RWD domain containing 4.
   
   0.824
rbm48
RNA binding motif protein 48.
    
 
 0.797
smpdl3a
Sphingomyelin phosphodiesterase, acid-like 3A.
      
 0.726
med31
Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.670
nudt14
Nudix (nucleoside diphosphate linked moiety X)-type motif 14.
      
 0.592
clg6h12orf4
Zgc:154077.
      
 0.451
ppp1r21
Protein phosphatase 1, regulatory subunit 21.
      
 0.451
LOC103459991
Zgc:77058.
      
 0.427
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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