Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmem53Transmembrane protein 53. (297 aa)    
Predicted Functional Partners:
ogfod3
Urotensin-2 receptor 2.
      
 0.923
pigb
Mannosyltransferase.
      
 0.922
zdhhc6
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
      
 0.921
ndc1
NDC1 transmembrane nucleoporin.
      
 0.921
tmem209
Transmembrane protein 209.
      
 0.915
ENSPREP00000002918
Uncharacterized protein.
     
 
0.900
LOC103471035
Mothers against decapentaplegic homolog.
     
  0.900
smad9
Mothers against decapentaplegic homolog.
     
  0.900
LOC103466010
Uncharacterized protein.
     
 
0.900
smad1
Mothers against decapentaplegic homolog.
     
  0.900
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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