Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cnksr3Uncharacterized protein. (562 aa)    
Predicted Functional Partners:
ipcef1
PH domain-containing protein.
 
      0.899
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
    
 0.701
braf
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.701
LOC103469576
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.701
ENSPREP00000003217
Sterile alpha motif domain containing 10a.
    
 0.689
SAMD12
Sterile alpha motif domain containing 12.
    
 0.689
Ksr1
Protein kinase domain-containing protein.
    
 0.655
ENSPREP00000001309
Uncharacterized protein.
    
 0.655
ksr2
Kinase suppressor of ras 2.
    
 0.655
map2k5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
    
 0.621
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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