STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
usp37Ubiquitin carboxyl-terminal hydrolase. (957 aa)    
Predicted Functional Partners:
ruvbl1
RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
    
  0.957
psmc5
Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.
    
 0.936
LOC103475709
Androgen receptor.
    
 0.753
ar
Androgen receptor.
    
 0.753
fbxw11
F-box and WD repeat domain containing 11a.
    
 
 0.748
etf1
Eukaryotic translation termination factor 1b.
      
 0.714
stam2
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2.
    
 0.710
stam
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1.
    
 0.710
gfm1
Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...]
    
 
 0.650
ubb
Uncharacterized protein.
   
 0.642
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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