STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
apc2APC regulator of WNT signaling pathway 2. (2253 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 0.996
LOC103472282
Uncharacterized protein.
   
 0.986
LOC103456513
Uncharacterized protein.
   
 0.984
AXIN2
Axin 2.
   
 0.984
LOC103469222
Axin 2 (conductin, axil).
   
 0.984
axin1
Axin 1.
   
 0.984
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
  0.961
ENSPREP00000001400
Uncharacterized protein.
    
 0.959
dvl1
Dishevelled segment polarity protein 1a.
    
 0.959
dvl2
Dishevelled segment polarity protein 2.
    
 0.959
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.