STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nedd4E3 ubiquitin-protein ligase. (842 aa)    
Predicted Functional Partners:
rps27a
Ribosomal protein S27a.
    
  0.887
ndfip2
Nedd4 family interacting protein 2.
    
 
 0.883
ENSPREP00000024586
Angiomotin.
    
 0.869
gja1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    
 0.868
LOC103473856
Uncharacterized protein; Belongs to the synuclein family.
    
 
 0.814
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.804
sqstm1
Sequestosome 1.
    
 
 0.792
LOC103471208
Nedd4 family interacting protein 1.
    
 
 0.785
ndfip1
Nedd4 family interacting protein 1, like.
    
 
 0.785
sgk2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
   
 0.775
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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