STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103473427Rap guanine nucleotide exchange factor (GEF) 1b. (1200 aa)    
Predicted Functional Partners:
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.994
crk
CRK proto-oncogene, adaptor protein.
    
 0.994
ENSPREP00000023825
SH2 domain-containing protein.
    
 0.994
LOC103467749
Uncharacterized protein.
    
 0.982
LOC103464617
RAP1A, member of RAS oncogene family b.
    
 0.982
LOC103476312
Uncharacterized protein.
   
 0.974
grb2
Growth factor receptor-bound protein 2b.
    
 0.962
rhoq
Ras homolog family member Q.
    
 0.940
rap1b
Uncharacterized protein.
    
 0.837
LOC103477907
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
   
 0.762
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.