STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103473427Rap guanine nucleotide exchange factor (GEF) 1b. (1200 aa)    
Predicted Functional Partners:
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.992
crk
CRK proto-oncogene, adaptor protein.
    
 0.992
ENSPREP00000023825
SH2 domain-containing protein.
    
 0.992
LOC103476312
Uncharacterized protein.
    
 0.974
LOC103467749
Uncharacterized protein.
    
 0.971
rap1b
Uncharacterized protein.
    
 0.971
LOC103464617
RAP1A, member of RAS oncogene family b.
    
 0.971
rhoq
Ras homolog family member Q.
   
 0.955
grb2
Growth factor receptor-bound protein 2b.
   
 0.881
bcar1
BCAR1 scaffold protein, Cas family member.
    
 0.782
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.