ska3 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

ska3

Spindle and kinetochore associated complex subunit 3. (523 aa)

Predicted Functional Partners:

ska1

0.995

Ska2

0.992

spc25

0.945

nuf2

0.940

ndc80

0.938

ttk

0.909

exo1

0.883

spc24

0.875

ENSPREP00000027387

0.819

ENSPREP00000027385

0.775

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000027385	Ska2	ENSPREP00000027385	ENSPREP00000024605	Uncharacterized protein.	SKA2 domain-containing protein.	0.624
ENSPREP00000027385	ska1	ENSPREP00000027385	ENSPREP00000009257	Uncharacterized protein.	Uncharacterized protein.	0.890
ENSPREP00000027385	ska3	ENSPREP00000027385	ENSPREP00000001078	Uncharacterized protein.	Spindle and kinetochore associated complex subunit 3.	0.775
ENSPREP00000027387	exo1	ENSPREP00000027387	ENSPREP00000027206	PP1-binding domain-containing protein.	Exonuclease 1.	0.410
ENSPREP00000027387	ndc80	ENSPREP00000027387	ENSPREP00000028925	PP1-binding domain-containing protein.	NDC80 kinetochore complex component.	0.781
ENSPREP00000027387	nuf2	ENSPREP00000027387	ENSPREP00000030246	PP1-binding domain-containing protein.	UF2 component of NDC80 kinetochore complex.	0.894
ENSPREP00000027387	ska1	ENSPREP00000027387	ENSPREP00000009257	PP1-binding domain-containing protein.	Uncharacterized protein.	0.511
ENSPREP00000027387	ska3	ENSPREP00000027387	ENSPREP00000001078	PP1-binding domain-containing protein.	Spindle and kinetochore associated complex subunit 3.	0.819
ENSPREP00000027387	spc25	ENSPREP00000027387	ENSPREP00000010568	PP1-binding domain-containing protein.	SPC25 component of NDC80 kinetochore complex.	0.698
ENSPREP00000027387	ttk	ENSPREP00000027387	ENSPREP00000022549	PP1-binding domain-containing protein.	Ttk protein kinase.	0.899
Ska2	ENSPREP00000027385	ENSPREP00000024605	ENSPREP00000027385	SKA2 domain-containing protein.	Uncharacterized protein.	0.624
Ska2	ndc80	ENSPREP00000024605	ENSPREP00000028925	SKA2 domain-containing protein.	NDC80 kinetochore complex component.	0.729
Ska2	nuf2	ENSPREP00000024605	ENSPREP00000030246	SKA2 domain-containing protein.	UF2 component of NDC80 kinetochore complex.	0.650
Ska2	ska1	ENSPREP00000024605	ENSPREP00000009257	SKA2 domain-containing protein.	Uncharacterized protein.	0.996
Ska2	ska3	ENSPREP00000024605	ENSPREP00000001078	SKA2 domain-containing protein.	Spindle and kinetochore associated complex subunit 3.	0.992
Ska2	spc24	ENSPREP00000024605	ENSPREP00000021899	SKA2 domain-containing protein.	SPC24 component of NDC80 kinetochore complex.	0.690
exo1	ENSPREP00000027387	ENSPREP00000027206	ENSPREP00000027387	Exonuclease 1.	PP1-binding domain-containing protein.	0.410
exo1	ndc80	ENSPREP00000027206	ENSPREP00000028925	Exonuclease 1.	NDC80 kinetochore complex component.	0.631
exo1	nuf2	ENSPREP00000027206	ENSPREP00000030246	Exonuclease 1.	UF2 component of NDC80 kinetochore complex.	0.907
exo1	ska1	ENSPREP00000027206	ENSPREP00000009257	Exonuclease 1.	Uncharacterized protein.	0.533