tbc1d9 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

tbc1d9

TBC1 domain family, member 9 (with GRAM domain). (1276 aa)

Predicted Functional Partners:

gak

0.622

ap5m1

0.607

vegfc

0.520

bysl

0.502

susd1

0.502

snapin

0.500

atp5mc3

0.498

blm

0.474

igf2r

0.472

hip1

0.471

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ap5m1	gak	ENSPREP00000015875	ENSPREP00000012671	Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.	Cyclin G associated kinase.	0.806
ap5m1	igf2r	ENSPREP00000015875	ENSPREP00000026805	Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.	Insulin-like growth factor 2 receptor.	0.492
ap5m1	susd1	ENSPREP00000015875	ENSPREP00000025463	Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.	Sushi domain containing 1.	0.622
ap5m1	tbc1d9	ENSPREP00000015875	ENSPREP00000001165	Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.	TBC1 domain family, member 9 (with GRAM domain).	0.607
atp5mc3	tbc1d9	ENSPREP00000007730	ENSPREP00000001165	ATP synthase membrane subunit c locus 2; Belongs to the ATPase C chain family.	TBC1 domain family, member 9 (with GRAM domain).	0.498
blm	tbc1d9	ENSPREP00000011311	ENSPREP00000001165	BLM RecQ like helicase.	TBC1 domain family, member 9 (with GRAM domain).	0.474
bysl	tbc1d9	ENSPREP00000006398	ENSPREP00000001165	Bystin-like.	TBC1 domain family, member 9 (with GRAM domain).	0.502
gak	ap5m1	ENSPREP00000012671	ENSPREP00000015875	Cyclin G associated kinase.	Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.	0.806
gak	hip1	ENSPREP00000012671	ENSPREP00000027388	Cyclin G associated kinase.	Huntingtin interacting protein 1.	0.980
gak	igf2r	ENSPREP00000012671	ENSPREP00000026805	Cyclin G associated kinase.	Insulin-like growth factor 2 receptor.	0.887
gak	snapin	ENSPREP00000012671	ENSPREP00000029846	Cyclin G associated kinase.	SNAP associated protein.	0.635
gak	tbc1d9	ENSPREP00000012671	ENSPREP00000001165	Cyclin G associated kinase.	TBC1 domain family, member 9 (with GRAM domain).	0.622
hip1	gak	ENSPREP00000027388	ENSPREP00000012671	Huntingtin interacting protein 1.	Cyclin G associated kinase.	0.980
hip1	igf2r	ENSPREP00000027388	ENSPREP00000026805	Huntingtin interacting protein 1.	Insulin-like growth factor 2 receptor.	0.600
hip1	snapin	ENSPREP00000027388	ENSPREP00000029846	Huntingtin interacting protein 1.	SNAP associated protein.	0.560
hip1	tbc1d9	ENSPREP00000027388	ENSPREP00000001165	Huntingtin interacting protein 1.	TBC1 domain family, member 9 (with GRAM domain).	0.471
igf2r	ap5m1	ENSPREP00000026805	ENSPREP00000015875	Insulin-like growth factor 2 receptor.	Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family.	0.492
igf2r	gak	ENSPREP00000026805	ENSPREP00000012671	Insulin-like growth factor 2 receptor.	Cyclin G associated kinase.	0.887
igf2r	hip1	ENSPREP00000026805	ENSPREP00000027388	Insulin-like growth factor 2 receptor.	Huntingtin interacting protein 1.	0.600
igf2r	snapin	ENSPREP00000026805	ENSPREP00000029846	Insulin-like growth factor 2 receptor.	SNAP associated protein.	0.558