itpa protein (Poecilia reticulata) - STRING interaction network

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itpa

Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (195 aa)

Predicted Functional Partners:

nme7

0.969

nme6

0.968

tpmt

0.958

LOC103482172

0.956

LOC103469013

0.956

nme3

0.956

LOC103469155

0.954

atic

0.952

gmps

0.951

dut

0.950

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103469013	LOC103469155	ENSPREP00000017608	ENSPREP00000024280	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.955
LOC103469013	LOC103482172	ENSPREP00000017608	ENSPREP00000006159	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.901
LOC103469013	dut	ENSPREP00000017608	ENSPREP00000012958	NDK domain-containing protein; Belongs to the NDK family.	Deoxyuridine triphosphatase.	0.934
LOC103469013	itpa	ENSPREP00000017608	ENSPREP00000001180	NDK domain-containing protein; Belongs to the NDK family.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.956
LOC103469013	nme3	ENSPREP00000017608	ENSPREP00000022314	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.901
LOC103469013	nme6	ENSPREP00000017608	ENSPREP00000028503	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.922
LOC103469013	nme7	ENSPREP00000017608	ENSPREP00000025049	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase 7; Belongs to the NDK family.	0.911
LOC103469155	LOC103469013	ENSPREP00000024280	ENSPREP00000017608	Nucleoside diphosphate kinase.	NDK domain-containing protein; Belongs to the NDK family.	0.955
LOC103469155	LOC103482172	ENSPREP00000024280	ENSPREP00000006159	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase.	0.954
LOC103469155	dut	ENSPREP00000024280	ENSPREP00000012958	Nucleoside diphosphate kinase.	Deoxyuridine triphosphatase.	0.934
LOC103469155	itpa	ENSPREP00000024280	ENSPREP00000001180	Nucleoside diphosphate kinase.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.954
LOC103469155	nme3	ENSPREP00000024280	ENSPREP00000022314	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase.	0.955
LOC103469155	nme6	ENSPREP00000024280	ENSPREP00000028503	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase.	0.948
LOC103469155	nme7	ENSPREP00000024280	ENSPREP00000025049	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase 7; Belongs to the NDK family.	0.917
LOC103482172	LOC103469013	ENSPREP00000006159	ENSPREP00000017608	Nucleoside diphosphate kinase.	NDK domain-containing protein; Belongs to the NDK family.	0.901
LOC103482172	LOC103469155	ENSPREP00000006159	ENSPREP00000024280	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase.	0.954
LOC103482172	dut	ENSPREP00000006159	ENSPREP00000012958	Nucleoside diphosphate kinase.	Deoxyuridine triphosphatase.	0.934
LOC103482172	itpa	ENSPREP00000006159	ENSPREP00000001180	Nucleoside diphosphate kinase.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.956
LOC103482172	nme3	ENSPREP00000006159	ENSPREP00000022314	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase.	0.901
LOC103482172	nme6	ENSPREP00000006159	ENSPREP00000028503	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase.	0.920

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