foxa2 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

foxa2

Forkhead box A2. (423 aa)

Predicted Functional Partners:

sox17

0.924

LOC103471993

0.865

tbxt

0.865

gata6

0.813

gata4

0.812

mixl1

0.798

LOC103475709

0.791

ar

0.791

LOC103458082

0.730

esr1

0.730

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103458082	esr1	ENSPREP00000003460	ENSPREP00000006015	Estrogen receptor 2b.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.910
LOC103458082	foxa2	ENSPREP00000003460	ENSPREP00000001214	Estrogen receptor 2b.	Forkhead box A2.	0.730
LOC103458082	gata4	ENSPREP00000003460	ENSPREP00000029877	Estrogen receptor 2b.	GATA binding protein 4.	0.487
LOC103471993	foxa2	ENSPREP00000021918	ENSPREP00000001214	T-box transcription factor Ta.	Forkhead box A2.	0.865
LOC103471993	gata4	ENSPREP00000021918	ENSPREP00000029877	T-box transcription factor Ta.	GATA binding protein 4.	0.750
LOC103471993	gata6	ENSPREP00000021918	ENSPREP00000025542	T-box transcription factor Ta.	GATA binding protein 6.	0.732
LOC103471993	mixl1	ENSPREP00000021918	ENSPREP00000001861	T-box transcription factor Ta.	Mix paired-like homeobox.	0.887
LOC103471993	sox17	ENSPREP00000021918	ENSPREP00000004912	T-box transcription factor Ta.	SRY-box transcription factor 17.	0.797
LOC103475709	ar	ENSPREP00000030777	ENSPREP00000031253	Androgen receptor.	Androgen receptor.	0.902
LOC103475709	esr1	ENSPREP00000030777	ENSPREP00000006015	Androgen receptor.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.510
LOC103475709	foxa2	ENSPREP00000030777	ENSPREP00000001214	Androgen receptor.	Forkhead box A2.	0.791
LOC103475709	gata4	ENSPREP00000030777	ENSPREP00000029877	Androgen receptor.	GATA binding protein 4.	0.489
ar	LOC103475709	ENSPREP00000031253	ENSPREP00000030777	Androgen receptor.	Androgen receptor.	0.902
ar	esr1	ENSPREP00000031253	ENSPREP00000006015	Androgen receptor.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.543
ar	foxa2	ENSPREP00000031253	ENSPREP00000001214	Androgen receptor.	Forkhead box A2.	0.791
ar	gata4	ENSPREP00000031253	ENSPREP00000029877	Androgen receptor.	GATA binding protein 4.	0.553
esr1	LOC103458082	ENSPREP00000006015	ENSPREP00000003460	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Estrogen receptor 2b.	0.910
esr1	LOC103475709	ENSPREP00000006015	ENSPREP00000030777	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Androgen receptor.	0.510
esr1	ar	ENSPREP00000006015	ENSPREP00000031253	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Androgen receptor.	0.543
esr1	foxa2	ENSPREP00000006015	ENSPREP00000001214	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Forkhead box A2.	0.730