pax1 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

pax1

Paired box 1a. (358 aa)

Predicted Functional Partners:

meox2

0.653

msx1

0.600

LOC103460172

0.557

ENSPREP00000034241

0.541

hoxa3

0.523

zmynd10

0.519

meox1

0.498

dlx2

0.495

LOC103466968

0.482

comp

0.465

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000034241	pax1	ENSPREP00000034241	ENSPREP00000001240	Paired box 10.	Paired box 1a.	0.541
LOC103460172	pax1	ENSPREP00000015449	ENSPREP00000001240	Uncharacterized protein.	Paired box 1a.	0.557
LOC103466968	pax1	ENSPREP00000012124	ENSPREP00000001240	Homeobox domain-containing protein.	Paired box 1a.	0.482
comp	pax1	ENSPREP00000000763	ENSPREP00000001240	Cartilage oligomeric matrix protein.	Paired box 1a.	0.465
dlx2	pax1	ENSPREP00000006391	ENSPREP00000001240	Distal-less homeobox 2b.	Paired box 1a.	0.495
hoxa3	pax1	ENSPREP00000000744	ENSPREP00000001240	Homeobox A4a.	Paired box 1a.	0.523
meox1	meox2	ENSPREP00000017336	ENSPREP00000031030	Mesenchyme homeobox 1.	Mesenchyme homeobox 2a.	0.944
meox1	pax1	ENSPREP00000017336	ENSPREP00000001240	Mesenchyme homeobox 1.	Paired box 1a.	0.498
meox2	meox1	ENSPREP00000031030	ENSPREP00000017336	Mesenchyme homeobox 2a.	Mesenchyme homeobox 1.	0.944
meox2	msx1	ENSPREP00000031030	ENSPREP00000001376	Mesenchyme homeobox 2a.	Muscle segment homeobox 1a.	0.440
meox2	pax1	ENSPREP00000031030	ENSPREP00000001240	Mesenchyme homeobox 2a.	Paired box 1a.	0.653
msx1	meox2	ENSPREP00000001376	ENSPREP00000031030	Muscle segment homeobox 1a.	Mesenchyme homeobox 2a.	0.440
msx1	pax1	ENSPREP00000001376	ENSPREP00000001240	Muscle segment homeobox 1a.	Paired box 1a.	0.600
pax1	ENSPREP00000034241	ENSPREP00000001240	ENSPREP00000034241	Paired box 1a.	Paired box 10.	0.541
pax1	LOC103460172	ENSPREP00000001240	ENSPREP00000015449	Paired box 1a.	Uncharacterized protein.	0.557
pax1	LOC103466968	ENSPREP00000001240	ENSPREP00000012124	Paired box 1a.	Homeobox domain-containing protein.	0.482
pax1	comp	ENSPREP00000001240	ENSPREP00000000763	Paired box 1a.	Cartilage oligomeric matrix protein.	0.465
pax1	dlx2	ENSPREP00000001240	ENSPREP00000006391	Paired box 1a.	Distal-less homeobox 2b.	0.495
pax1	hoxa3	ENSPREP00000001240	ENSPREP00000000744	Paired box 1a.	Homeobox A4a.	0.523
pax1	meox1	ENSPREP00000001240	ENSPREP00000017336	Paired box 1a.	Mesenchyme homeobox 1.	0.498