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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP19Matrix metallopeptidase 19. (468 aa)    
Predicted Functional Partners:
LOC103468846
TIMP metallopeptidase inhibitor 2b.
   
 0.614
LOC103481516
TIMP metallopeptidase inhibitor 2a.
   
 0.614
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.547
timp4
TIMP metallopeptidase inhibitor 4, tandem duplicate 1.
    
 0.455
nid2
Nidogen 2a (osteonidogen).
     
 0.425
nid1
Nidogen 1a.
     
 0.425
ENSPREP00000021829
Uncharacterized protein.
     
 0.425
ENSPREP00000021839
Thyroglobulin type-1 domain-containing protein.
     
 0.425
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.