VANGL2 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

VANGL2

VANGL planar cell polarity protein 2. (691 aa)

Predicted Functional Partners:

dvl2

0.964

ENSPREP00000001242

0.956

ENSPREP00000020826

0.956

PRICKLE1

0.904

LOC103459444

0.904

prickle2

0.904

LOC103467536

0.894

LOC103467721

0.869

ror1

0.591

dvl1

0.586

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000001242	ENSPREP00000020826	ENSPREP00000001242	ENSPREP00000020826	DIX domain-containing protein.	DIX domain-containing protein.	0.901
ENSPREP00000001242	LOC103459444	ENSPREP00000001242	ENSPREP00000016949	DIX domain-containing protein.	Prickle homolog 1b.	0.958
ENSPREP00000001242	LOC103467536	ENSPREP00000001242	ENSPREP00000024091	DIX domain-containing protein.	Prickle homolog 2a.	0.958
ENSPREP00000001242	LOC103467721	ENSPREP00000001242	ENSPREP00000003457	DIX domain-containing protein.	Prickle homolog 3.	0.958
ENSPREP00000001242	PRICKLE1	ENSPREP00000001242	ENSPREP00000014207	DIX domain-containing protein.	Prickle homolog 1a.	0.958
ENSPREP00000001242	VANGL2	ENSPREP00000001242	ENSPREP00000001301	DIX domain-containing protein.	VANGL planar cell polarity protein 2.	0.956
ENSPREP00000001242	dvl2	ENSPREP00000001242	ENSPREP00000018043	DIX domain-containing protein.	Dishevelled segment polarity protein 2.	0.910
ENSPREP00000001242	prickle2	ENSPREP00000001242	ENSPREP00000027598	DIX domain-containing protein.	Prickle homolog 2b.	0.958
ENSPREP00000020826	ENSPREP00000001242	ENSPREP00000020826	ENSPREP00000001242	DIX domain-containing protein.	DIX domain-containing protein.	0.901
ENSPREP00000020826	LOC103459444	ENSPREP00000020826	ENSPREP00000016949	DIX domain-containing protein.	Prickle homolog 1b.	0.958
ENSPREP00000020826	LOC103467536	ENSPREP00000020826	ENSPREP00000024091	DIX domain-containing protein.	Prickle homolog 2a.	0.958
ENSPREP00000020826	LOC103467721	ENSPREP00000020826	ENSPREP00000003457	DIX domain-containing protein.	Prickle homolog 3.	0.958
ENSPREP00000020826	PRICKLE1	ENSPREP00000020826	ENSPREP00000014207	DIX domain-containing protein.	Prickle homolog 1a.	0.958
ENSPREP00000020826	VANGL2	ENSPREP00000020826	ENSPREP00000001301	DIX domain-containing protein.	VANGL planar cell polarity protein 2.	0.956
ENSPREP00000020826	dvl2	ENSPREP00000020826	ENSPREP00000018043	DIX domain-containing protein.	Dishevelled segment polarity protein 2.	0.910
ENSPREP00000020826	prickle2	ENSPREP00000020826	ENSPREP00000027598	DIX domain-containing protein.	Prickle homolog 2b.	0.958
LOC103459444	ENSPREP00000001242	ENSPREP00000016949	ENSPREP00000001242	Prickle homolog 1b.	DIX domain-containing protein.	0.958
LOC103459444	ENSPREP00000020826	ENSPREP00000016949	ENSPREP00000020826	Prickle homolog 1b.	DIX domain-containing protein.	0.958
LOC103459444	VANGL2	ENSPREP00000016949	ENSPREP00000001301	Prickle homolog 1b.	VANGL planar cell polarity protein 2.	0.904
LOC103459444	dvl1	ENSPREP00000016949	ENSPREP00000004961	Prickle homolog 1b.	Dishevelled segment polarity protein 1a.	0.617