NCSTN protein (Poecilia reticulata) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

NCSTN

Nicastrin. (699 aa)

Predicted Functional Partners:

aph1a

0.997

psenen

0.996

psen2

0.994

LOC103473440

0.980

notch1

0.980

LOC103458271

0.974

LOC103468742

0.925

LOC103463625

0.925

app

0.899

LOC103459816

0.899

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103458271	LOC103459816	ENSPREP00000012922	ENSPREP00000033442	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Amyloid beta (A4) precursor protein b.	0.726
LOC103458271	LOC103473440	ENSPREP00000012922	ENSPREP00000002570	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Notch receptor 1a.	0.798
LOC103458271	NCSTN	ENSPREP00000012922	ENSPREP00000001339	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Nicastrin.	0.974
LOC103458271	aph1a	ENSPREP00000012922	ENSPREP00000027328	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	APH1B gamma secretase subunit.	0.970
LOC103458271	app	ENSPREP00000012922	ENSPREP00000014569	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Amyloid beta (A4) precursor protein a.	0.726
LOC103458271	notch1	ENSPREP00000012922	ENSPREP00000009635	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Notch receptor 1b.	0.798
LOC103458271	psen2	ENSPREP00000012922	ENSPREP00000007303	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.451
LOC103458271	psenen	ENSPREP00000012922	ENSPREP00000005239	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	Uncharacterized protein.	0.978
LOC103459816	LOC103458271	ENSPREP00000033442	ENSPREP00000012922	Amyloid beta (A4) precursor protein b.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.726
LOC103459816	NCSTN	ENSPREP00000033442	ENSPREP00000001339	Amyloid beta (A4) precursor protein b.	Nicastrin.	0.899
LOC103459816	aph1a	ENSPREP00000033442	ENSPREP00000027328	Amyloid beta (A4) precursor protein b.	APH1B gamma secretase subunit.	0.619
LOC103459816	psen2	ENSPREP00000033442	ENSPREP00000007303	Amyloid beta (A4) precursor protein b.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.726
LOC103459816	psenen	ENSPREP00000033442	ENSPREP00000005239	Amyloid beta (A4) precursor protein b.	Uncharacterized protein.	0.710
LOC103463625	NCSTN	ENSPREP00000013783	ENSPREP00000001339	Notch receptor 2.	Nicastrin.	0.925
LOC103463625	aph1a	ENSPREP00000013783	ENSPREP00000027328	Notch receptor 2.	APH1B gamma secretase subunit.	0.916
LOC103463625	psen2	ENSPREP00000013783	ENSPREP00000007303	Notch receptor 2.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.922
LOC103468742	NCSTN	ENSPREP00000008958	ENSPREP00000001339	Notch receptor 3.	Nicastrin.	0.925
LOC103468742	aph1a	ENSPREP00000008958	ENSPREP00000027328	Notch receptor 3.	APH1B gamma secretase subunit.	0.916
LOC103468742	psen2	ENSPREP00000008958	ENSPREP00000007303	Notch receptor 3.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.923
LOC103473440	LOC103458271	ENSPREP00000002570	ENSPREP00000012922	Notch receptor 1a.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.798