STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rab27aRAB27A, member RAS oncogene family. (163 aa)    
Predicted Functional Partners:
LOC103481063
Melanophilin a.
    
 0.857
sytl1
Synaptotagmin-like 1.
   
 0.812
LOC103474215
Synaptotagmin-like 2b.
   
 0.812
rabggta
Rab geranylgeranyltransferase subunit alpha.
    
 0.788
LOC103459897
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.762
Sytl3
RabBD domain-containing protein.
    
 0.735
sytl5
Synaptotagmin-like 5.
    
 0.735
madd
MAP-kinase activating death domain.
     
 0.692
ENSPREP00000001090
Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family.
     
 0.674
myo5a
Myosin VAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.628
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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