STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
irf5Interferon regulatory factor 5. (474 aa)    
Predicted Functional Partners:
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.960
LOC103466287
SCY domain-containing protein.
     
  0.900
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.718
tlr3
Toll-like receptor 3; Belongs to the Toll-like receptor family.
   
 0.594
ENSPREP00000005404
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
    
 0.591
aldh8a1
Aldehyde dehydrogenase 8 family, member A1; Belongs to the aldehyde dehydrogenase family.
    
 
 0.586
LOC103465382
Signal transducer and activator of transcription.
    
 0.564
ENSPREP00000003814
RING-type domain-containing protein.
    
 0.553
trim25
Tripartite motif containing 25.
    
 0.553
il10
Interleukin 10.
   
 
 0.542
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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