STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103466227Phospholipase A2, group XV. (416 aa)    
Predicted Functional Partners:
LOC103473607
Uncharacterized protein.
     
 0.937
LOC103469577
Patatin-like phospholipase domain containing 7b.
     
 0.937
pnpla6
Patatin-like phospholipase domain containing 6.
     
 0.923
ENSPREP00000013858
Uncharacterized protein.
     
 0.916
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
     
 0.910
ppard
Peroxisome proliferator-activated receptor delta b.
     
 0.908
gpcpd1
Glycerophosphocholine phosphodiesterase 1.
     
 0.905
lcat
Lecithin-cholesterol acyltransferase.
  
  
 
0.903
LOC103463466
Uncharacterized protein.
   
 
 0.860
pla2g6
Phospholipase A2, group VI (cytosolic, calcium-independent).
     
 0.849
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.