LOC103466227 protein (Poecilia reticulata) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

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gene co-occurrence

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protein homology

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Score

LOC103466227

Phospholipase A2, group XV. (416 aa)

Predicted Functional Partners:

LOC103473607

0.926

pnpla6

0.920

lpcat2

0.916

ENSPREP00000013858

0.907

lpcat3

0.904

lcat

0.903

ENSPREP00000012104

0.777

pla2g4a

0.775

LOC103463466

0.765

LOC103477850

0.748

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000012104	ENSPREP00000013858	ENSPREP00000012104	ENSPREP00000013858	Phospholipase A(2).	Uncharacterized protein.	0.737
ENSPREP00000012104	LOC103463466	ENSPREP00000012104	ENSPREP00000004853	Phospholipase A(2).	Uncharacterized protein.	0.956
ENSPREP00000012104	LOC103466227	ENSPREP00000012104	ENSPREP00000001377	Phospholipase A(2).	Phospholipase A2, group XV.	0.777
ENSPREP00000012104	LOC103473607	ENSPREP00000012104	ENSPREP00000011458	Phospholipase A(2).	Uncharacterized protein.	0.654
ENSPREP00000012104	lpcat2	ENSPREP00000012104	ENSPREP00000009043	Phospholipase A(2).	Lysophosphatidylcholine acyltransferase 2.	0.905
ENSPREP00000012104	pla2g4a	ENSPREP00000012104	ENSPREP00000013432	Phospholipase A(2).	Phospholipase A2.	0.976
ENSPREP00000012104	pnpla6	ENSPREP00000012104	ENSPREP00000000374	Phospholipase A(2).	Patatin-like phospholipase domain containing 6.	0.654
ENSPREP00000013858	ENSPREP00000012104	ENSPREP00000013858	ENSPREP00000012104	Uncharacterized protein.	Phospholipase A(2).	0.737
ENSPREP00000013858	LOC103463466	ENSPREP00000013858	ENSPREP00000004853	Uncharacterized protein.	Uncharacterized protein.	0.650
ENSPREP00000013858	LOC103466227	ENSPREP00000013858	ENSPREP00000001377	Uncharacterized protein.	Phospholipase A2, group XV.	0.907
ENSPREP00000013858	LOC103473607	ENSPREP00000013858	ENSPREP00000011458	Uncharacterized protein.	Uncharacterized protein.	0.907
ENSPREP00000013858	lcat	ENSPREP00000013858	ENSPREP00000001363	Uncharacterized protein.	Lecithin-cholesterol acyltransferase.	0.909
ENSPREP00000013858	lpcat2	ENSPREP00000013858	ENSPREP00000009043	Uncharacterized protein.	Lysophosphatidylcholine acyltransferase 2.	0.905
ENSPREP00000013858	lpcat3	ENSPREP00000013858	ENSPREP00000017841	Uncharacterized protein.	Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family.	0.913
ENSPREP00000013858	pla2g4a	ENSPREP00000013858	ENSPREP00000013432	Uncharacterized protein.	Phospholipase A2.	0.669
ENSPREP00000013858	pnpla6	ENSPREP00000013858	ENSPREP00000000374	Uncharacterized protein.	Patatin-like phospholipase domain containing 6.	0.906
LOC103463466	ENSPREP00000012104	ENSPREP00000004853	ENSPREP00000012104	Uncharacterized protein.	Phospholipase A(2).	0.956
LOC103463466	ENSPREP00000013858	ENSPREP00000004853	ENSPREP00000013858	Uncharacterized protein.	Uncharacterized protein.	0.650
LOC103463466	LOC103466227	ENSPREP00000004853	ENSPREP00000001377	Uncharacterized protein.	Phospholipase A2, group XV.	0.765
LOC103463466	LOC103473607	ENSPREP00000004853	ENSPREP00000011458	Uncharacterized protein.	Uncharacterized protein.	0.660

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Network Stats

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Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006796

Phosphate-containing compound metabolic process

8 of 941

1.07

1.08

7.32e-05

GO:0006470

Protein dephosphorylation

3 of 67

1.8

1.07

0.0074

GO:0036211

Protein modification process

7 of 1176

0.92

0.7

0.0034

GO:0006468

Protein phosphorylation

4 of 415

1.13

0.57

0.0437

GO:1901564

Organonitrogen compound metabolic process

8 of 2532

0.64

0.41

0.0241

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0017018

Myosin phosphatase activity

3 of 45

1.97

1.16

0.0058

GO:0140096

Catalytic activity, acting on a protein

7 of 1272

0.89

0.64

0.0058

GO:0004672

Protein kinase activity

4 of 415

1.13

0.59

0.0390

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:556

Mixed, incl. GDP metabolic process, and Signaling receptor complex adaptor activity

3 of 5

2.92

2.59

1.88e-05

CL:1988

Mixed, incl. Serine/Threonine Kinase AGC, catalytic domain, and PI3K Cascade

4 of 32

2.24

2.42

1.88e-05

CL:1900

Mixed, incl. Serine/threonine-protein kinase, and MAPK cascade

5 of 137

1.71

2.01

2.10e-05

CL:1990

Mixed, incl. Serine/Threonine Kinase AGC, catalytic domain, and PI3K Cascade

3 of 26

2.21

1.84

0.00029

CL:13390

Cyclic nucleotide-dependent protein kinase activity, and PPM-type phosphatase, divalent cation binding

2 of 6

2.67

1.43

0.0025

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000719

Protein kinase domain

8 of 394

1.45

2.15

1.07e-07

IPR011009

Protein kinase-like domain superfamily

8 of 431

1.41

2.07

1.08e-07

IPR036457

PPM-type phosphatase-like domain superfamily

3 of 30

2.14

1.45

0.0017

IPR001932

PPM-type phosphatase-like domain

3 of 30

2.14

1.45

0.0017

IPR000222

PPM-type phosphatase, divalent cation binding

2 of 12

2.37

0.84

0.0285

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00331

Sigma factor PP2C-like phosphatases

2 of 22

2.1

0.73

0.0449

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