osbpl3 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

osbpl3

Oxysterol-binding protein; Belongs to the OSBP family. (787 aa)

Predicted Functional Partners:

gak

0.596

apaf1

0.503

casp9

0.503

vapa

0.499

LOC103464667

0.499

ndufa12

0.484

agbl5

0.477

abca12

0.473

abcf1

0.469

LOC103468029

0.466

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103464667	osbpl3	ENSPREP00000016218	ENSPREP00000001406	VAMP (vesicle-associated membrane protein)-associated protein B and C.	Oxysterol-binding protein; Belongs to the OSBP family.	0.499
LOC103468029	osbpl3	ENSPREP00000001710	ENSPREP00000001406	MSP domain-containing protein.	Oxysterol-binding protein; Belongs to the OSBP family.	0.466
abca12	abcf1	ENSPREP00000017654	ENSPREP00000017984	ATP-binding cassette, sub-family A (ABC1), member 12.	ATP-binding cassette, sub-family F (GCN20), member 1.	0.456
abca12	osbpl3	ENSPREP00000017654	ENSPREP00000001406	ATP-binding cassette, sub-family A (ABC1), member 12.	Oxysterol-binding protein; Belongs to the OSBP family.	0.473
abcf1	abca12	ENSPREP00000017984	ENSPREP00000017654	ATP-binding cassette, sub-family F (GCN20), member 1.	ATP-binding cassette, sub-family A (ABC1), member 12.	0.456
abcf1	ndufa12	ENSPREP00000017984	ENSPREP00000033476	ATP-binding cassette, sub-family F (GCN20), member 1.	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.726
abcf1	osbpl3	ENSPREP00000017984	ENSPREP00000001406	ATP-binding cassette, sub-family F (GCN20), member 1.	Oxysterol-binding protein; Belongs to the OSBP family.	0.469
agbl5	osbpl3	ENSPREP00000025616	ENSPREP00000001406	ATP/GTP binding protein-like 5.	Oxysterol-binding protein; Belongs to the OSBP family.	0.477
apaf1	casp9	ENSPREP00000001466	ENSPREP00000019950	Apoptotic peptidase activating factor 1.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.999
apaf1	ndufa12	ENSPREP00000001466	ENSPREP00000033476	Apoptotic peptidase activating factor 1.	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.479
apaf1	osbpl3	ENSPREP00000001466	ENSPREP00000001406	Apoptotic peptidase activating factor 1.	Oxysterol-binding protein; Belongs to the OSBP family.	0.503
casp9	apaf1	ENSPREP00000019950	ENSPREP00000001466	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Apoptotic peptidase activating factor 1.	0.999
casp9	osbpl3	ENSPREP00000019950	ENSPREP00000001406	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	Oxysterol-binding protein; Belongs to the OSBP family.	0.503
gak	osbpl3	ENSPREP00000012671	ENSPREP00000001406	Cyclin G associated kinase.	Oxysterol-binding protein; Belongs to the OSBP family.	0.596
ndufa12	abcf1	ENSPREP00000033476	ENSPREP00000017984	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	ATP-binding cassette, sub-family F (GCN20), member 1.	0.726
ndufa12	apaf1	ENSPREP00000033476	ENSPREP00000001466	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	Apoptotic peptidase activating factor 1.	0.479
ndufa12	osbpl3	ENSPREP00000033476	ENSPREP00000001406	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	Oxysterol-binding protein; Belongs to the OSBP family.	0.484
osbpl3	LOC103464667	ENSPREP00000001406	ENSPREP00000016218	Oxysterol-binding protein; Belongs to the OSBP family.	VAMP (vesicle-associated membrane protein)-associated protein B and C.	0.499
osbpl3	LOC103468029	ENSPREP00000001406	ENSPREP00000001710	Oxysterol-binding protein; Belongs to the OSBP family.	MSP domain-containing protein.	0.466
osbpl3	abca12	ENSPREP00000001406	ENSPREP00000017654	Oxysterol-binding protein; Belongs to the OSBP family.	ATP-binding cassette, sub-family A (ABC1), member 12.	0.473