STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP3Caspase 3; Belongs to the peptidase C14A family. (292 aa)    
Predicted Functional Partners:
birc2
Baculoviral IAP repeat containing 2.
   
 0.973
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
0.970
LOC103478931
Uncharacterized protein; Belongs to the peptidase C14A family.
  
0.968
LOC103459939
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
  
0.965
LOC108167062
Uncharacterized protein; Belongs to the peptidase C14A family.
  
0.957
sptan1
Spectrin alpha, non-erythrocytic 1.
   
 0.956
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
 0.955
LOC103478932
Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
0.953
LOC103481969
Baculoviral IAP repeat containing 5a.
   
 0.947
stk3
Serine/threonine kinase 3 (STE20 homolog, yeast).
   
  0.946
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.