fa2h protein (Poecilia reticulata) - STRING interaction network

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fa2h

Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (381 aa)

Predicted Functional Partners:

ENSPREP00000015100

0.779

LOC103462495

0.779

agmo

0.775

ENSPREP00000002275

0.765

LOC103460312

0.758

LOC103478806

0.739

mrpl37

0.716

sc5d

0.709

msmo1

0.687

ch25h

0.687

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002275	fa2h	ENSPREP00000002275	ENSPREP00000001544	DED domain-containing protein.	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]	0.765
ENSPREP00000015100	LOC103478806	ENSPREP00000015100	ENSPREP00000025960	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Cytochrome b5 reductase 4.	0.866
ENSPREP00000015100	ch25h	ENSPREP00000015100	ENSPREP00000002111	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.	0.487
ENSPREP00000015100	fa2h	ENSPREP00000015100	ENSPREP00000001544	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]	0.779
ENSPREP00000015100	msmo1	ENSPREP00000015100	ENSPREP00000000110	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	Methylsterol monooxygenase 1; Belongs to the sterol desaturase family.	0.487
LOC103460312	LOC103478806	ENSPREP00000020961	ENSPREP00000025960	Cytochrome b5 domain containing 1; Belongs to the cytochrome b5 family.	Cytochrome b5 reductase 4.	0.805
LOC103460312	fa2h	ENSPREP00000020961	ENSPREP00000001544	Cytochrome b5 domain containing 1; Belongs to the cytochrome b5 family.	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]	0.758
LOC103462495	LOC103478806	ENSPREP00000034259	ENSPREP00000025960	Cytochrome b5 type B; Belongs to the cytochrome b5 family.	Cytochrome b5 reductase 4.	0.836
LOC103462495	ch25h	ENSPREP00000034259	ENSPREP00000002111	Cytochrome b5 type B; Belongs to the cytochrome b5 family.	Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.	0.487
LOC103462495	fa2h	ENSPREP00000034259	ENSPREP00000001544	Cytochrome b5 type B; Belongs to the cytochrome b5 family.	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]	0.779
LOC103462495	msmo1	ENSPREP00000034259	ENSPREP00000000110	Cytochrome b5 type B; Belongs to the cytochrome b5 family.	Methylsterol monooxygenase 1; Belongs to the sterol desaturase family.	0.487
LOC103478806	ENSPREP00000015100	ENSPREP00000025960	ENSPREP00000015100	Cytochrome b5 reductase 4.	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	0.866
LOC103478806	LOC103460312	ENSPREP00000025960	ENSPREP00000020961	Cytochrome b5 reductase 4.	Cytochrome b5 domain containing 1; Belongs to the cytochrome b5 family.	0.805
LOC103478806	LOC103462495	ENSPREP00000025960	ENSPREP00000034259	Cytochrome b5 reductase 4.	Cytochrome b5 type B; Belongs to the cytochrome b5 family.	0.836
LOC103478806	fa2h	ENSPREP00000025960	ENSPREP00000001544	Cytochrome b5 reductase 4.	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]	0.739
LOC103478806	mrpl37	ENSPREP00000025960	ENSPREP00000015721	Cytochrome b5 reductase 4.	Mitochondrial ribosomal protein L37.	0.805
agmo	fa2h	ENSPREP00000031056	ENSPREP00000001544	Alkylglycerol monooxygenase; Belongs to the sterol desaturase family.	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]	0.775
ch25h	ENSPREP00000015100	ENSPREP00000002111	ENSPREP00000015100	Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.	Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family.	0.487
ch25h	LOC103462495	ENSPREP00000002111	ENSPREP00000034259	Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.	Cytochrome b5 type B; Belongs to the cytochrome b5 family.	0.487
ch25h	fa2h	ENSPREP00000002111	ENSPREP00000001544	Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]	0.687

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