acy1 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

acy1

Aminoacylase 1. (419 aa)

Predicted Functional Partners:

otc

0.970

arg2

0.922

LOC103481893

0.922

ENSPREP00000012813

0.896

ASS1

0.837

ppme1

0.806

ttc1

0.789

agmat

0.710

dpyd

0.687

GLO1

0.680

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASS1	LOC103481893	ENSPREP00000022473	ENSPREP00000023975	Argininosuccinate synthase 1.	Arginase.	0.517
ASS1	acy1	ENSPREP00000022473	ENSPREP00000001610	Argininosuccinate synthase 1.	Aminoacylase 1.	0.837
ASS1	agmat	ENSPREP00000022473	ENSPREP00000032893	Argininosuccinate synthase 1.	Agmatine ureohydrolase (agmatinase); Belongs to the arginase family.	0.615
ASS1	arg2	ENSPREP00000022473	ENSPREP00000013679	Argininosuccinate synthase 1.	Arginase.	0.517
ASS1	otc	ENSPREP00000022473	ENSPREP00000015067	Argininosuccinate synthase 1.	Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	0.999
ENSPREP00000012813	acy1	ENSPREP00000012813	ENSPREP00000001610	Nudix (nucleoside diphosphate linked moiety X)-type motif 1.	Aminoacylase 1.	0.896
GLO1	acy1	ENSPREP00000006093	ENSPREP00000001610	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	Aminoacylase 1.	0.680
LOC103481893	ASS1	ENSPREP00000023975	ENSPREP00000022473	Arginase.	Argininosuccinate synthase 1.	0.517
LOC103481893	acy1	ENSPREP00000023975	ENSPREP00000001610	Arginase.	Aminoacylase 1.	0.922
LOC103481893	arg2	ENSPREP00000023975	ENSPREP00000013679	Arginase.	Arginase.	0.903
LOC103481893	otc	ENSPREP00000023975	ENSPREP00000015067	Arginase.	Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	0.987
acy1	ASS1	ENSPREP00000001610	ENSPREP00000022473	Aminoacylase 1.	Argininosuccinate synthase 1.	0.837
acy1	ENSPREP00000012813	ENSPREP00000001610	ENSPREP00000012813	Aminoacylase 1.	Nudix (nucleoside diphosphate linked moiety X)-type motif 1.	0.896
acy1	GLO1	ENSPREP00000001610	ENSPREP00000006093	Aminoacylase 1.	Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.	0.680
acy1	LOC103481893	ENSPREP00000001610	ENSPREP00000023975	Aminoacylase 1.	Arginase.	0.922
acy1	agmat	ENSPREP00000001610	ENSPREP00000032893	Aminoacylase 1.	Agmatine ureohydrolase (agmatinase); Belongs to the arginase family.	0.710
acy1	arg2	ENSPREP00000001610	ENSPREP00000013679	Aminoacylase 1.	Arginase.	0.922
acy1	dpyd	ENSPREP00000001610	ENSPREP00000021733	Aminoacylase 1.	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	0.687
acy1	otc	ENSPREP00000001610	ENSPREP00000015067	Aminoacylase 1.	Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	0.970
acy1	ppme1	ENSPREP00000001610	ENSPREP00000031451	Aminoacylase 1.	Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.	0.806