STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nudt21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (229 aa)    
Predicted Functional Partners:
Pcf11
CID domain-containing protein.
    
 0.993
cpsf6
Cleavage and polyadenylation specific factor 6.
   
 0.985
CPSF7
Cleavage and polyadenylation specific factor 7.
   
 0.978
ENSPREP00000018529
FIP1 like 1b (S. cerevisiae).
   
 0.977
cpsf4
Cleavage and polyadenylation specific factor 4.
    
 0.958
cstf2
Cleavage stimulation factor, 3' pre-RNA, subunit 2.
   
 0.935
cstf1
Cleavage stimulation factor, 3' pre-RNA, subunit 1.
     
 0.922
cpsf2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.921
eif4a3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
   
 
 0.904
WDR33
WD repeat domain 33.
     
 0.896
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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