STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
znf277Zinc finger protein 277. (445 aa)    
Predicted Functional Partners:
LOC103472243
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
   0.844
rsrc2
Arginine/serine-rich coiled-coil 2.
    
 
 0.804
pdcd2
Programmed cell death 2.
   
 
 0.785
pdcd2l
Programmed cell death 2-like.
   
 
 0.753
tmem186
Transmembrane protein 186.
      
 0.669
znf622
Zinc finger protein 622.
   
  
 0.654
zmat2
Zinc finger, matrin-type 2.
      
 0.604
tmem258
Transmembrane protein 258.
      
 0.597
sf3a2
Splicing factor 3a, subunit 2.
      
 0.595
pex6
Peroxisomal biogenesis factor 6.
      
 0.544
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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