ucp1 protein (Poecilia reticulata) - STRING interaction network

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Score

ucp1

Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (305 aa)

Predicted Functional Partners:

prdm16

0.725

PPARG

0.679

sirt5

0.603

Sirt7

0.599

LOC103459286

0.570

adipor1

0.570

sod2

0.551

LOC103473021

0.547

lipe

0.547

ENSPREP00000002706

0.546

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000002706	ucp1	ENSPREP00000002706	ENSPREP00000001751	Neuropeptide Y.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.546
LOC103459286	adipor1	ENSPREP00000006883	ENSPREP00000020848	Adiponectin receptor 2.	Adiponectin receptor 1a.	0.901
LOC103459286	ucp1	ENSPREP00000006883	ENSPREP00000001751	Adiponectin receptor 2.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.570
LOC103473021	PPARG	ENSPREP00000013233	ENSPREP00000009292	Lipase, hormone-sensitive a.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.548
LOC103473021	lipe	ENSPREP00000013233	ENSPREP00000021641	Lipase, hormone-sensitive a.	Lipase, hormone-sensitive b.	0.901
LOC103473021	prdm16	ENSPREP00000013233	ENSPREP00000033841	Lipase, hormone-sensitive a.	Si:ch211-263k4.2.	0.414
LOC103473021	ucp1	ENSPREP00000013233	ENSPREP00000001751	Lipase, hormone-sensitive a.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.547
PPARG	LOC103473021	ENSPREP00000009292	ENSPREP00000013233	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Lipase, hormone-sensitive a.	0.548
PPARG	lipe	ENSPREP00000009292	ENSPREP00000021641	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Lipase, hormone-sensitive b.	0.548
PPARG	prdm16	ENSPREP00000009292	ENSPREP00000033841	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Si:ch211-263k4.2.	0.640
PPARG	sod2	ENSPREP00000009292	ENSPREP00000008085	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.510
PPARG	ucp1	ENSPREP00000009292	ENSPREP00000001751	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.679
Sirt7	sirt5	ENSPREP00000000575	ENSPREP00000014162	Uncharacterized protein.	NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.	0.602
Sirt7	sod2	ENSPREP00000000575	ENSPREP00000008085	Uncharacterized protein.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.666
Sirt7	ucp1	ENSPREP00000000575	ENSPREP00000001751	Uncharacterized protein.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.599
adipor1	LOC103459286	ENSPREP00000020848	ENSPREP00000006883	Adiponectin receptor 1a.	Adiponectin receptor 2.	0.901
adipor1	ucp1	ENSPREP00000020848	ENSPREP00000001751	Adiponectin receptor 1a.	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.570
lipe	LOC103473021	ENSPREP00000021641	ENSPREP00000013233	Lipase, hormone-sensitive b.	Lipase, hormone-sensitive a.	0.901
lipe	PPARG	ENSPREP00000021641	ENSPREP00000009292	Lipase, hormone-sensitive b.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.548
lipe	prdm16	ENSPREP00000021641	ENSPREP00000033841	Lipase, hormone-sensitive b.	Si:ch211-263k4.2.	0.414